Comparative investigation on the activity of a synthetic corticotrophin (18-ACTH). A clinical trial.
نویسندگان
چکیده
The effect of the administration of a synthetic peptide with corticotrophic properties (18-ACTH) on the plasma corticosteroid levels of 72 healthy volunteers was studied. The same effect is seen both after subcutaneous and intramuscular injection. Intravenous administration provokes a longer lasting influence on adrenocortical activity, especially when large doses of the peptide are given; side effects however plead against this method of stimulation of the adrenal cortex. Discrepancies are reported between results from the fluorometric and radioimmuno assay of corticosteroids.
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ورودعنوان ژورنال:
- Zeitschrift fur klinische Chemie und klinische Biochemie
دوره 12 8 شماره
صفحات -
تاریخ انتشار 1974